Natural Progesterone USP 5% Lotion

Natural Progesterone USP 5%

Average 10 drop application contains 14 milligrams of progesterone

ClearPatch Progesterone USP 5% Lotion is a transdermal preparation containing 50 mg/ml of progesterone (1.4 mg per average drop). Progesterone is fully dissolved and easily absorbable.

Ingredients: blend of natural oils (coconut, grape seed, jojoba, safflower, sunflower), vitamin E, ethyl alcohol, isopropyl palmitate, Natural Progesterone USP from yams (1500 mg/oz), natural essential oils of sweet orange and rose geranium. Contains no parabens.

Applications per container: One-ounce bottle delivers about 200 5-drop applications (7 mg progesterone per application). With a daily dose of 10 drops, it will last 5 months (21 consecutive days per month) or 7 months (14 consecutive days per month).

ClearPatch® Lotion:  the Clear Advantage
    • Transdermal application allows much lower doses to produce results similar to larger oral ones because it avoids first-pass liver metabolism; it does not unnecessarily overburdens the liver.  Absorption occurs over longer period of time preventing sharp increases of progesterone blood level

    • Excellent transdermal absorption - absorbs readily from skin surface

    • Progesterone is 100% dissolved and fully bioavailable

    • Ease of use: required dose is contained in a small amount of lotion, which can be inconspicuously applied any time.  Dose measurement is achieved by counting drops

    • Convenience: small 1-ounce bottle easily fits in purse

  • Human-friendly ingredients, including essential oils of sweet orange and rose geranium, which are also used in aromatherapy for PMS and menopausal complaints

Consulting your health care professional is recommended before using this product

An appropriate dose is the minimal amount that alleviates hormonal imbalance symptoms. The following suggested doses are intended to restore physiological level of progesterone, therefore restoring its balance in relation to estrogen. ClearPatch Progesterone 5% Lotion can be applied once (in the morning) or twice a day (in the morning and before retiring). In most cases it is better to use twice a day. If the late evening application causes undesired increase of energy, apply the lotion no later than 4 hours before bedtime.

Dr. John R. Lee and other authors* recommend using progesterone for:

Menopause or postmenopause:
2 – 10 drops once or twice daily for 21 days; discontinue for 7 days and repeat. If discontinuation causes difficult to tolerate reoccurrence of symptoms, the break can be shortened to 3 days. The break is necessary to maintain the sensitivity of progesterone receptors, as well as to prevent its possible buildup in the body. If you have never used progesterone and do not know how much your body requires for balance, start using 2 drops twice daily. Increase the dose gradually until symptoms subside or disappear. Do not exceed 15 drops per day without consulting your doctor. After 1 - 2 months try decreasing the number of drops to find the correct dose for your body. Use the smallest dose at which symptoms don’t reoccur.

Women who do not menstruate can also use an easier to remember alternative application schedule: use the lotion for 25 days of the calendar month and discontinue for the rest of the month.

Premenopause or PMS:
Start using in the middle of your cycle between the 10-th and 12-th day depending on the cycle's length. First day of cycle is the first day of menstruation. Use 2 - 10 drops once or twice daily for 14 days. When irregular cycles cause earlier menstruation, discontinue using until the middle of next cycle. According to Dr. Lee*, cycles should become normalized after 2 - 3 months of usage. Insufficient progesterone level in the body causes reduced sensitivity of estrogen receptors. Initial progesterone supplementation restores their sensitivity, which may cause some women to experience certain symptoms related to estrogen dominance: water retention, headache and enlarged breasts. It is important to remember that these symptoms will disappear in two weeks to two months*. To avoid the symptoms we recommend starting with a lower dose, gradually increasing it until the desired dose is reached.

Prevention of osteoporosis:
Follow one of the above schedules, apply twice a day. Keep in mind that slim, small, older women usually need less progesterone than younger women with greater body weight and that even a minimal dose is beneficial.

Men: Average daily dose is 2 - 4 drops. Do not exceed 6 drops per day without consulting your heath care professional. Use for 3 consecutive weeks, discontinue for 1 week and repeat. Alternatively, use for 25 days in a month, discontinue for the rest of the month and repeat the cycle.

How and where to apply: Invert bottle holding it vertically for proper drop delivery. Gently massage to thin skin areas: palms, inner arms, chest, neck or backside of the knees. It is best to alternate between application sites. Apply to clean skin only. Do not apply other lotions or creams to the area of ClearPatch application - they can reduce progesterone absorption.

When to expect results?
Improvement can be noticed after a few days of progesterone supplementation, depending on symptoms. In case of substantial progesterone deficiency, a few weeks might be necessary for the symptoms to subside.

How long to use natural progesterone?
As long as you need its benefits. If you are using hormone replacement therapy (HRT) and want to switch to health-promoting natural progesterone, Dr. Lee* recommends complete discontinuation of synthetic progestins if your therapy includes them, and reducing estrogen dose by half then gradually taper off if possible. Many women can discontinue using estrogens after several months of natural progesterone supplementation. For more information refer to the books suggested below.

Do not use progesterone while using hormone-based birth control. Consult a doctor in case of a serious health condition, taking prescription medication, when using hormonal therapy, pregnant, planning to become pregnant or nursing.

* Information in this publication is based on the following books, which offer detailed explanation of women's and men's hormone balance issues, hormone balance programs, as well as detailed descriptions of how to use natural hormones. Although most of the information in the books has been provided for women, they contain a wealth of information applicable to men:

John R. Lee, M.D. What Your Doctor May Not Tell You About Menopause: The Breakthrough Book on Natural Progesterone.

John R. Lee, M.D. What Your Doctor May Not Tell You About Premenopause: Balance Your Hormones and Life from Thirty to Fifty.

John R. Lee, M.D. Hormone Balance for Men. Available online at

Uzzi Reiss, M.D. Natural Hormone Balance.

Jonathan V. Wright, M.D. Natural Hormone Replacement.

Joseph McWherter, M.D. Avoiding Breast Cancer While Balancing Your Hormones.

For external use only. Avoid contact with eyes.
Keep out of reach of children.
Store at room temperature away from strong sources of heat and light.

Information in this publication is not intended to replace any medical treatment
prescribed by your physician.
For those with chronic medical problems
or taking a regularly prescribed medication, please consult your health care practitioner.

All providers of natural remedies are required to post the following:

Statements in this publication have not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.

Information for California residents

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